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The Institutional Review Board for Public Health (IRBPH) is an administrative body established to protect the rights and welfare of human research subjects recruited to participate in research activities or data collected on human subjects conducted under the auspices of the Department of Health with which it is affiliated. The IRBPH has the authority to approve, require modifications in, or disapprove all research activities that fall within its jurisdiction, as specified by federal regulations and local institutional policy. Research that has been reviewed and approved by an IRB may be subject to review and disapproval by Department of Health (DOH) officials. However, DOH officials may not approve research if it has been disapproved by the IRB [Federal Policy section 112].
The IRBPH functions independently of but in coordination with other communities. For example, an institution (e.g., university, hospital, government body, research institute) may have a research committee that reviews protocols to determine whether the institution should support the proposed research. The IRBPH, however, makes its independent determination whether to approve or disapprove the protocol based upon whether or not human subjects are adequately protected.
Under the Office of Human Research Protections (OHRP) within the US Department of Health and Human Services (DHHS), the District of Columbia Department of Health houses the Institutional Review Board for the Public Health (IRBPH) Number: 1–00002318, IORG Number: 0001841, Federalwide Assurance Number: 00003034.